Glia in health and disease

Student projects

 

Literature Thesis opportunity available

Wanted: highly motivated student interested in the effects of stress on social behavior.

High levels of stress or chronic stress can have long term consequences and plays an important role in the aetiology of a broad range of disorders such as autism spectrum disorders, schizophrenia and depression. How stress affects you is dependent on whether you are male or female and whether you experienced the stress prenatally, as a child, or as an adult. This effect of sex and timing is also present in animal models used to study these disorders, but are hardly ever a focus point, even though it may provide important insights into the development of these disorders. By performing a systematic review on animal studies we will try to elucidate the effects of sex and timing on one of the most detrimental behavioural deficits seen in patients with neurodevelopmental and neuropsychiatric disorders: social behaviour. The student may become co-author on this prospective peer reviewed paper. If you are interested please email: Dit e-mailadres wordt beveiligd tegen spambots. JavaScript dient ingeschakeld te zijn om het te bekijken.

 

General information

Highly motivated master students, who are eager to learn more about glia biology, are welcome to join our research group for 6-9 months for a student project. 

If you have a background in biomedical sciences you can apply for an internship by sending your CV and motivation letter to Dit e-mailadres wordt beveiligd tegen spambots. JavaScript dient ingeschakeld te zijn om het te bekijken..

You will work together with one of our post-docs or PhD-students on a specific glia-related research question. Because of this one-to-one guidance and support, only a limited number projects are available.

 

A literature thesis will be supervised by a member of the Hol lab. Several topics are available and the precise focus of you thesis can be discussed with Dit e-mailadres wordt beveiligd tegen spambots. JavaScript dient ingeschakeld te zijn om het te bekijken..   

 

 

Subjects for a literature thesis
  • Astrocytes physiology and pathology
  • Glia in brain disease
  • Neural stem cells in brain diseae
  • Molecular and cell biology of brain tumours (focus on astrocytoma)
  • Molecular and cellular changes induced by stroke
  • Intermediate filament system in brain disease