Glia in health and disease

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Recent Publications

          • Ormel PR, Vieira de Sá R, van Bodegraven EJ, Karst H, Harschnitz O, Sneeboer MAM, Johansen LE, van Dijk RE, Scheefhals N, Berdenis van Berlekom A, Ribes Martínez E, Kling S, MacGillavry HD, van den Berg LH, Kahn RS, Hol EM, de Witte LD, Pasterkamp RJMicroglia innately develop within cerebral organoids. 
            Nature Communicatons 2018  
          • Antonovaite N, Beekmans SV, Hol EM, Wadman WJ, Iannuzzi D.Regional variations in stiffness in live mouse brain tissue determined by depth-controlled indentation mapping. 
            Sci Reports 2018  
          • Oosterhof N, Kuil LE, van der Linde HC, Burm SM, Berdowski W, van Ijcken WFJ, van Swieten JC, Hol EM, Verheijen MHG, van Ham TJ.Colony-Stimulating Factor 1 Receptor (CSF1R) Regulates Microglia Density and Distribution, but Not Microglia Differentiation In Vivo. 
            Cell Reports 2018  
          • Hillen AEJ, Burbach JPH, Hol EMCell adhesion and matricellular support by astrocytes of the tripartite synapse 
            Prog Neurobiology 2018  
          • Hol and Capetanaki Type III Intermediate Filaments Desmin, Glial Fibrillary Acidic Protein (GFAP), Vimentin, and Peripherin 
            Cold Spring Harb Perspect Biol. 2017 Dec 1  
          • Stassen O.M.J.A., van Bodegraven E.J. et al. GFAPδ/GFAPα ratio directs astrocytoma gene expression towards a more malignant profile
            Oncotarget  
          • Ormel P.R. et al. Characterization of macrophages from schizophrenia patients.
            NPJ Schizophr  
          • Iorio R. et al. Clinical and immunological characteristics of the spectrum of GFAP autoimmunity: a case series of 22 patients
            J Neurol Neurosurg Psychiatry
          • Yin, Z. et al. Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease 
            Neurobiol Aging
          • van Kesteren C.F. et al. Immune involvement in the pathogenesis of schizophrenia: a meta-analysis on postmortem brain studies
            Transl Psychiatry  
          • van Reemst K. et al. The Indispensable Roles of Microglia and Astrocytes during Brain Development
            Frontiers Human Neuroscience  

 

Grants

      • 2017 November - Jinte Middeldorp received BCRM young talent fellowship
      • 2017 July - ZonMW Memorabel collaboration with UMCG, VU and VUMC - Glia in dementia
      • 2017 July - ZonMW TAS - Human sdult neural stem cells